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Zbigniew J. Witczak Click Chemistry in Glycoscience


Lays the foundation for new methods and applications of carbohydrate click chemistry Introduced by K. Barry Sharpless of The Scripps Research Institute in 2001, click chemistry mimics nature, giving researchers the tools needed to generate new substances quickly and reliably by joining small units together. With contributions from more than thirty pioneering researchers in the field, this text explores the many promising applications of click chemistry in glycoscience. Readers will learn both the basic concepts of carbohydrate click chemistry as well as its many biomedical applications, including synthetic antigens, analogs of cell-surface receptors, immobilized enzymes, targeted drug delivery systems, and multivalent cancer vaccines. Click Chemistry in Glycoscience examines a broad range of methodologies and strategies that have emerged from this rapidly evolving field. Each chapter describes new approaches, ideas, consequences, and applications resulting from the introduction of click processes. Divided into four sections, the book covers: Click chemistry strategies and decoupling Thio-click chemistry of carbohydrates Carbohydrate click chemistry for novel synthetic targets Carbohydrate click chemistry in biomedical sciences Thoroughly researched, the book reflects the most recent findings published in the literature. Diagrams and figures throughout the book enable readers to more easily grasp complex concepts and reaction processes. At the end of each chapter, references lead to the primary literature for further investigation of individual topics. The application of click chemistry to carbohydrates has tremendous implications for research. With this book as their guide, researchers have a solid foundation from which they can develop new methods and applications of carbohydrate click chemistry, including new carbohydrate-based therapeutics.

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Joerg Lahann Click Chemistry for Biotechnology and Materials Science


Mimicking natural biochemical processes, click chemistry is a modular approach to organic synthesis, joining together small chemical units quickly, efficiently and predictably. In contrast to complex traditional synthesis, click reactions offer high selectivity and yields, near-perfect reliability and exceptional tolerance towards a wide range of functional groups and reaction conditions. These ‘spring loaded’ reactions are achieved by using a high thermodynamic driving force, and are attracting tremendous attention throughout the chemical community. Originally introduced with the focus on drug discovery, the concept has been successfully applied to materials science, polymer chemistry and biotechnology. The first book to consider this topic, Click Chemistry for Biotechnology and Materials Science examines the fundamentals of click chemistry, its application to the precise design and synthesis of macromolecules, and its numerous applications in materials science and biotechnology. The book surveys the current research, discusses emerging trends and future applications, and provides an important nucleation point for research. Edited by one of the top 100 young innovators with the greatest potential to have an impact on technology in the 21st century according to Technology Review and with contributions from pioneers in the field, Click Chemistry for Biotechnology and Materials Science provides an ideal reference for anyone wanting to learn more about click reactions.

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Joerg Lahann Click Chemistry for Biotechnology and Materials Science


Mimicking natural biochemical processes, click chemistry is a modular approach to organic synthesis, joining together small chemical units quickly, efficiently and predictably. In contrast to complex traditional synthesis, click reactions offer high selectivity and yields, near-perfect reliability and exceptional tolerance towards a wide range of functional groups and reaction conditions. These ‘spring loaded’ reactions are achieved by using a high thermodynamic driving force, and are attracting tremendous attention throughout the chemical community. Originally introduced with the focus on drug discovery, the concept has been successfully applied to materials science, polymer chemistry and biotechnology. The first book to consider this topic, Click Chemistry for Biotechnology and Materials Science examines the fundamentals of click chemistry, its application to the precise design and synthesis of macromolecules, and its numerous applications in materials science and biotechnology. The book surveys the current research, discusses emerging trends and future applications, and provides an important nucleation point for research. Edited by one of the top 100 young innovators with the greatest potential to have an impact on technology in the 21st century according to Technology Review and with contributions from pioneers in the field, Click Chemistry for Biotechnology and Materials Science provides an ideal reference for anyone wanting to learn more about click reactions.

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Группа авторов Macrocyclic and Supramolecular Chemistry


This book commemorates the 25th anniversary of the International Izatt-Christensen Award in Macrocyclic and Supramolecular Chemistry. The award, one of the most prestigious of small awards in chemistry, recognizes excellence in the developing field of macrocyclic and supramolecular chemistry Macrocyclic and Supramolecular Chemistry: How Izatt-Christensen Award Winners Shaped the Field features chapters written by the award recipients who provide unique perspectives on the spectacular growth in these expanding and vibrant fields of chemistry over the past half century, and on the role of these awardees in shaping this growth. During this time there has been an upsurge of interest in the design, synthesis and characterization of increasingly more complex macrocyclic ligands and in the application of this knowledge to understanding molecular recognition processes in host-guest chemistry in ways that were scarcely envisioned decades earlier. In October 2016, Professor Jean-Pierre Sauvage and Sir J. Fraser Stoddart (author for chapter 22 «Contractile and Extensile Molecular Systems: Towards Molecular Muscles» by Jean -Pierre Sauvage, Vincent Duplan, and Frédéric Niess and 20 «Serendipity» by Paul R. McGonigal and J. Fraser Stoddart respectively) were awarded the Nobel Prize in Chemistry alongside fellow Wiley author Bernard Feringa, for the design and synthesis of molecular machines.

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Sason Shaik S. Chemistry as a Game of Molecular Construction


Chemistry as a Game of Molecular Construction: The Bond-Click Way utilizes an innovative and engaging approach to introduce students to the basic concepts and universal aspects of chemistry, with an emphasis on molecules’ beauty and their importance in our lives. • Offers a unique approach that portrays chemistry as a window into mankind’s material-chemical essence • Reveals the beauty of molecules through the “click” method, a teaching methodology comprised of the process of constructing molecules from building blocks • Styles molecular construction in a way that reveals the universal aspect of chemistry • Allows students to construct molecules, from the simple hydrogen molecule all the way to complex strands of DNA, thereby showing the overarching unity of matter • Provides problems sets and solutions for each chapter

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Группа авторов Progress in Inorganic Chemistry


Cutting-edge research and innovative science PROGRESS in Inorganic Chemistry Hailed by professional chemists as an index of the most influential and current research being done in inorganic chemistry, Progress in Inorganic Chemistry has also enjoyed the reputation as an indispensable working reference. Featuring the work of internationally renowned chemists, this newest volume provides a clear, authoritative examination of each critically new advance and innovative tremor in inorganic chemistry today. «This series is a valuable addition to the library of the practicing research chemist, and is a good starting point for students wishing to understand modern inorganic chemistry.» –Canadian Chemical News «[This series] has won a deservedly honored place on the bookshelf of the chemist attempting to keep afloat in the torrent of original papers on inorganic chemistry.» –Chemistry in Britain CONTENTS OF VOLUME 42 * Slow Proton-Transfer Reactions in Organometallic and Bioinorganic Chemistry (K. W. Kramarz and J. R. Norton, Colorado State University) * Higher Oligopyridines as a Structural Motif in Metallosupramolecular Chemistry (Edwin C. Constable, Universitat Basel) * Ternary Transition Metal Sulfides (Bryan W. Eichhorn, University of Maryland) * Organoimido Complexes of the Transition Metals (David E. Wigley, University of Arizona) * Palladium Complex Catalyzed Oxidation Reactions (Andreas Heumann, Klaus-Joachim Jens, and Marius Reglier, Universite d'Aix-Marseille)

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Группа авторов Progress in Inorganic Chemistry


Innovation today . . . Practice tomorrow. PROGRESS in Inorganic Chemistry Today's cutting-edge chemical experimentation is a foretaste of the technical arsenal of tomorrow's chemist. Progress in Inorganic Chemistry affords instant and convenient access to every area of innovative chemical research and has long served as the professional chemist's index to the newest and influential turns in inorganic chemistry. Featuring the work of internationally renowned chemists, Volume 45 discusses: * Selective Recognition of Organic Molecules by Metallohosts (James W. Canary and Bruce C. Gibb, New York University) * Metallacrowns: A New Class of Molecular Recognition Agents (Vincent L. Pecoraro, Ann J. Stemmler, Brian R. Gibney, Jeffrey J. Bodwin, Hsin Wang, Jeff W. Kampf, and Almut Barwinski, University of Michigan) * The Interpretation of Ligand Field Parameters (Adam J. Bridgeman and Malcolm Gerloch, University Chemical Laboratories) * Chemistry of Transition Metal Cyanide Compounds: Modern Perspectives (Kim R. Dunbar and Robert A. Heintz, Michigan State University) * Assembling Sugars and Metals: Novel Architectures and Reactivities in Transition Metal Chemistry (Umberto Piarulli and Carlo Floriani, University of Lausanne) * Oxygen Activation Mechanism at the Binuclear Site of Heme-Copper Oxidase Superfamily as Revealed by Time-Resolved Resonance Raman Spectroscopy (Teizo Kitagawa and Takashi Ogura, Institute for Molecular Science) «This series is distinguished not only by its scope and breadth, but also by the depth and quality of the reviews.» –Journal of the American Chemical Society «This series is a valuable addition to the library of the practicing research chemist, and is a good starting point for students wishing to understand modern inorganic chemistry.» –Canadian Chemical News «[This series] has won a deservedly honored place on the bookshelf of the chemist attempting to keep afloat in the torrent of original papers on inorganic chemistry.» –Chemistry in Britain

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J C Roberts The Chemistry of Paper

Kenny Lipkowitz B. Reviews in Computational Chemistry


Computational chemistry is increasingly used in conjunction with organic, inorganic, medicinal, biological, physical, and analytical chemistry, biotechnology, materials science, and chemical physics. This series is essential in keeping those individuals involved in these fields abreast of recent developments in computational chemistry.

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Andrew J. Peacock Polymer Chemistry

Click Chemistry in Glycoscience | Wiley Online Books

ZBIGNIEW J. WITCZAK, PhD, is Professor in the Department of Pharmaceutical Sciences of the Nesbitt School of Pharmacy at Wilkes University. He has published over ninety research papers and holds six patents. His research focuses on carbohydrate synthons, including levoglucosenone and L-arabinose, as templates for carbohydrate-based therapeutics.

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Read "Click Chemistry in Glycoscience New Developments and Strategies" by Zbigniew J. Witczak available from Rakuten Kobo. Lays the foundation for new methods and applications of carbohydrate click chemistry Introduced by K. Barry Sharpless of...

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Zbigniew J. Witczak is the author of Click Chemistry in Glycoscience (0.0 avg rating, 0 ratings, 0 reviews, published 2013), Levoglucosenone and Levogluc...

Dr. Zbigniew J. Witczak - - Wilkes University

Zbigniew J. Witczak obtained his Ph.D. from Medical University of Lodz, Faculty of Pharmacy. Lodz, Poland. After postdoctoral work with Roy L. Whistler at Purdue University he briefly worked in industry (A. E. Staley) and joined in 1990 Faculty in School of Pharmacy at University of Connecticut. He moved to Wilkes University, Nesbitt School of Pharmacy in 2000 where he is Full Professor. He ...

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Buy Click Chemistry in Glycoscience: New Developments and Strategies 1 by Witczak, Zbigniew J., Bielski, Roman (ISBN: 9781118275337) from Amazon's Book Store. Everyday low prices and free delivery on eligible orders.

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《Click Chemistry in Glycoscience: New Developments and ...

《Click Chemistry in Glycoscience: New Developments and Strategies》(Zbigniew J. Witczak)内容简介: This book consists of a brief introduction, a foreword (provided by Professor Sharpless), and 13 c...

Zbigniew J Witczak (Author of Domino and Intramolecular ...

Zbigniew J Witczak is the author of Domino and Intramolecular Rearrangement Reactions as Advanced Synthetic Methods in Glycoscience (5.00 avg rating, 1 r...

Photoinduced Thiol−Ene Coupling as a Click Ligation Tool ...

Zbigniew J. Witczak. Thio-Click Approach to Glycomimetics. Phosphorus, Sulfur, and Silicon and the Related Elements 2013 , 188 (4) , 413-417.

Click Chemistry in Glycoscience: New Developments and ...

Click Chemistry in Glycoscience: New Developments and Strategies: Witczak, Zbigniew J., Bielski, Roman: Amazon.nl Selecteer uw cookievoorkeuren We gebruiken cookies en vergelijkbare tools om uw winkelervaring te verbeteren, onze services aan te bieden, te begrijpen hoe klanten onze services gebruiken zodat we verbeteringen kunnen aanbrengen, en om advertenties weer te geven.

Boston Therapeutics Appoints Zbigniew J. Witczak, Ph.D ...

Extensive Research Experience Adds Strength to Advisory Board. MANCHESTER, NH -- (Marketwired) -- 07/29/14 -- Boston Therapeutics, Inc. (OTCQB: BTHE), a developer of complex carbohydrate therapeutics to treat diabetes and inflammatory diseases, has appointed Zbigniew J. Witczak, Ph.D. to its Scientific Advisory Board (SAB).

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Witczak, Bielski, Roman Bielski: Click Chemistry in Glycoscienc - New Developments and Strategies. HC gerader Rücken kaschiert. Sprache: Englisch. (Buch (gebunden)) - bei eBook.de

101593326 - NLM Catalog Result

Author(s): Witczak,Zbigniew J,1947-; Bielski,Roman,1946- Title(s): Click chemistry in glycoscience : new developments and strategies/ edited by Zbigniew J. Witczak, Roman Bielski. Country of Publication: United States Publisher: Hoboken, N.J. : Wiley, c2013. Description: xxi, 375 p. : ill. Language: English ISBN: 9781118275337 (cloth) LCCN: 2012040254 MeSH: Click Chemistry/methods ...

Amazon.com: Zbigniew Witczak: Books

Click Chemistry in Glycoscience: New Developments and Strategies. by Zbigniew J. Witczak and Roman Bielski | Feb 5, 2013. 5.0 out of 5 stars 1. eTextbook $114.00 $ 114. 00 $142.50 $142.50. Available instantly. Hardcover $19.99 $ 19. 99 $142.50 $142.50. FREE Shipping. Only 1 left in stock - order soon. Carbohydrates in Drug Design. by Zbigniew Witczak | Jun 11, 1997. Hardcover $109.94 $ 109. 94 ...

- Wilkes University

Zbigniew J. Witczak obtained his Ph.D. from Medical University of Lodz, Faculty of Pharmacy. Lodz, Poland. After postdoctoral work with Roy L. Whistler at Purdue University he briefly worked in industry (A. E. Staley) and joined in 1990 Faculty in School of Pharmacy at University of Connecticut. He moved to Wilkes University, Nesbitt School of Pharmacy in 2000 where he is Full Professor. He ...

Cycloaddition of Cyclopentadiene to 3-Deoxy-1,2:5,6-di-O ...

Zbigniew J Witczak, Hong Chen, Peter Kaplon. Thio-sugars. Part 5: From d-glucal to 3-deoxy-(1→2)-2-S-thiodisaccharides through isolevoglucosenone—a simple approach. Tetrahedron: Asymmetry 2000, 11 (2) , 519-532. DOI: 10.1016/S0957-4166(99)00567-4. Zbigniew J. Witczak, Renu Chhabra, Hong Chen, Xiang-Qun Xie. Thiosugars II. A novel approach to thiodisaccharides The synthesis of 3-deoxy-4 ...

‪Zbigniew J. Witczak‬ - ‪Google Scholar‬

‪Professor & Chair Department of Pharmaceutical Sciences, Wilkes University‬ - ‪Cited by 2,185‬ - ‪medicinal chemistry‬ - ‪carbohydrate chemistry‬ - ‪organic chemistry‬ - ‪click chemistry‬ - ‪natural product chemistry‬

Zbigniew J. Witczak, Ph.D. of Wilkes University’s Nesbitt ...

Zbigniew J. Witczak, Ph.D., professor in the pharmaceutical sciences department in Wilkes University’s Nesbitt School of Pharmacy, has been selected to join the editorial board of the international journal Antibiotics. The open-access, peer-reviewed journal examins aspects of antibiotics and is published monthly by MDPI. Based in Basel, Switzerland, MDPI’s mission is to foster open ...

Carbohydrate Drug Design Acs Symposium Series

witczak zbigniew j platt david isbn 9780841239463 kostenloser versand fur this is an updated version of a chapter that previously appeared in carbohydrate drug design acs symposium series 932 edited by klyosov et al and published in 2006 acs symposium series carbohydrate drug design discusses pre clinical studies and clinical trials of carbohydrate based drugs drug delivery and pain ...

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Wyświetl profil użytkownika Zbigniew Witczak na LinkedIn, największej sieci zawodowej na świecie. Zbigniew Witczak ma 4 stanowiska w swoim profilu. Zobacz pełny profil użytkownika Zbigniew Witczak i odkryj jego/jej kontakty oraz stanowiska w podobnych firmach.

Click Chemistry in Glycoscience New Developments and ...

New Developments and Strategies, Click Chemistry in Glycoscience, Zbigniew J. Witczak, Roman Bielski, Wiley. Des milliers de livres avec la livraison chez vous en 1 jour ou en magasin avec -5% de réduction .

THIO-CLICK APPROACH TO GLYCOMIMICS. DESIGN AND SYNTHESIS ...

Zbigniew J. Witczak Neepa Patel. Department of Pharmaceutical Sciences, Wilkes University, Nesbitt School of Pharmacy, Wilkes-Barre, Pennsylvania, USA . During the last decade, Sharpless concept of click chemistry was transplanted to carbohydrate chemistry 1-3. While, the original alkyne-azide concept of click-chemistry is well known, the alternative thiol-click is relatively unexplored ...

Coupling and Decoupling of Diverse Molecular Units in ...

Zbigniew J. Witczak obtained his Ph.D. from Medical University of Lodz, Faculty of Pharmacy. Lodz, Poland. After a postdoctoral work with Roy L. Whistler at Purdue University he briefly worked in industry (A. E. Staley), and joined in 1990 the Faculty of the School of Pharmacy at the University of Connecticut. He moved to Wilkes University, Nesbitt School of Pharmacy in 2000, where he is a ...

Zbigniew J. Witczak · OverDrive: ebooks, audiobooks, and ...

Zbigniew J. Witczak obtained his Ph.D. from Medical University of Lodz, Faculty of Pharmacy (Poland). After postdoctoral work at Purdue University, he worked in industry (A. E.Staley), then?joined the faculty?of the?School of Pharmacy at Universit...

Author: Zbigniew J. Witczak - onlybooks.org

Author: Zbigniew J. Witczak. Click Chemistry In Glycoscience: ... Page 1 of 1 1. Genre

Carbohydrate Drug Design - Anatole A. Klyosov; Zbigniew J ...

Carbohydrate Drug Design Edited by Anatole A. Klyosov, Zbigniew J. Witczak, and David Platt. American Chemical Society. ACS Symposium Series. Carbohydrate Drug Design discusses pre-clinical studies and clinical trials of carbohydrate-based drugs, drug delivery and pain managements, biocompatibility, clearance and metabolic pathways of carbohydrate drugs, and actual medical devices employing ...

Boston Therapeutics Appoints Zbigniew J. Witczak, Ph.D ...

Boston Therapeutics, Inc. , a developer of complex carbohydrate therapeutics to treat diabetes and inflammatory diseases, has appointed Zbigniew J. Witczak, Ph.D. to its Scientific Advisory Board .

Books by Zbigniew J. Witczak

Zbigniew J. Witczak. J. W. · Zbigniew Witczak. Springer · Wiley. title media type ISBN-13 year of publica-tion other author(s) Click Chemistry in Glycoscience: New Developments and Strategies: Hardcover : 978-1-118-27533-7: 2013: Roman Bielski: Click Chemistry in Glycoscience: New Developments and Strategies: Printed Access Code : 978-1-118-52699-6: 2013 " Coupling and Decoupling of Diverse ...

Editorial [Hot Topic: Carbohydrate Chemistry (Guest Editor ...

Title: Editorial [Hot Topic: Carbohydrate Chemistry (Guest Editor: Zbigniew J. Witczak) ] VOLUME: 12 ISSUE: 12 Author(s):Zbigniew J. Witczak and Waldemar Priebe Affiliation:Department of Pharmaceutical Sciences Nesbitt School of Pharmacy, Wilkes University Wilkes-Barre, Pennsylvania 18766.

Coupling and Decoupling of Diverse Molecular Units in ...

Zbigniew J. Witczak obtained his Ph.D. from Medical University of Lodz, Faculty of Pharmacy. Lodz, Poland. After a postdoctoral work with Roy L. Whistler at Purdue University he briefly worked in industry (A. E. Staley), and joined in 1990 the Faculty of the School of Pharmacy at the University of Connecticut. He moved to Wilkes University, Nesbitt School of Pharmacy in 2000, where he is a ...

Click Chemistry Applied to Carbohydrate‐Based Drug ...

Click Chemistry Applied to Carbohydrate‐Based Drug Discovery. Vanessa Leiria Campo. Search for more papers by this author . Ivone Carvalho. Search for more papers by this author. Vanessa Leiria Campo. Search for more papers by this author. Ivone Carvalho. Search for more papers by this author. Book Editor(s): Zbigniew J. Witczak. Search for more papers by this author. Roman Bielski. Search ...

Click Chemistry in Glycoscience: New Developments and ...

Click Chemistry in Glycoscience: New Developments and Strategies - Zbigniew J. Witczak - 洋書の購入は楽天ブックスで。全品送料無料!購入毎に「楽天ポイント」が貯まってお得!みんなのレビュー・感想も満載。

Zbigniew Witczak Profiles | Facebook

View the profiles of people named Zbigniew Witczak. Join Facebook to connect with Zbigniew Witczak and others you may know. Facebook gives people the...

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Click Chemistry in Glycoscience - Zbigniew J. Witczak - Click Chemistry in Glycoscience - Zbigniew J. Witczak - The first text to focus on the application of click chemistry to glycoscience, this book discusses the therapeutic and pharmacological aspects of carbohydrate click chemistry and includes chapters on the concept's background, as well ...

Preface [Hot Topic: Carbohydrate Chemistry (Guest Editor ...

Title: Preface [Hot Topic: Carbohydrate Chemistry (Guest Editor: Zbigniew J. Witczak)] VOLUME: 8 ISSUE: 6 Author(s):Zbigniew J. Witczak Affiliation:Department of Pharmaceutical Sciences, Nesbitt School of Pharmacy, Wilkes UniversityWilkes-Barre, Pennsylvania 18766

Domino and Intramolecular Rearrangement Reactions as ...

Zbigniew J. Witczak, Roman Bielski. The book consists of a brief introduction, a foreward provided by professor Danishefsky of Columbia University, and about 14 – 16 chapters, each written by one or two eminent scholars/authors describing their recent research in the area of either domino reactions or intramolecular rearrangements in carbohydrate chemistry. Three or four chapters will be ...

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Zbigniew J. Witczak - WOOK

Zbigniew J. Witczak - consulte a biografia e bibliografia do autor de Domino And Intramolecular Rearrangement Reactions As Advanced Synthetic Methods In Glycoscience e Click Chemistry In Glycoscience

Carbohydrate Synthons in Natural Products Chemistry ...

Content: 1. Chiral Carbohydrate Building Blocks with a New Perspective: Revisited / Zbigniew J. Witczak -- 2. A Convenient Procedure for the Preparation of Levoglucosenone and Its Conversion to Novel Chiral Derivatives / Walter S. Trahanovsky, Jason M. Ochaoda, Chen Wang, Kevin D. Revell, Kirk B. Arvidson, Yu Wang, Huiyan Zhao, Steven Chung and Synthia Chang -- 3.

Coupling and Decoupling of Diverse Molecular Units in ...

Witczak, Zbigniew J. (et al.) ... Example of Sacrificial Unit Using Two Different Click Reactions in Coupling and Decoupling (CAD) Chemistry. Pages 299-307. Bielski, Roman (et al.) Preview. Increased Efficacy of NKT Cell-Adjuvanted Peptide Vaccines Through Chemical Conjugation. Pages 309-335 . Hayman, Colin M. (et al.) Preview. Show next xx. Read this book on SpringerLink Download Preface 1 ...

Zbigniew J. (zj) Witczak | Wilkes University | United ...

Zbigniew J. Witczak obtained his Ph.D. from Medical University of Lodz, Faculty of Pharmacy. Lodz, Poland. After postdoctoral work with Roy L. Whistler at Purdue University he briefly worked in industry (A. E. Staley) and joined in 1990 Faculty in School of Pharmacy at University of Connecticut. He moved to Wilkes University, Nesbitt School of Pharmacy in 2000 where he is Full Professor. He ...

Editorial [Hot Topic: Current Organic Chemistry Devoted to ...

Author(s):Zbigniew J. Witczak. Affiliation:Department of Pharmaceutical SciencesNesbitt School of Pharmacy, Wilkes UniversityWilkes-Barre, Pennsylvania 18766. Close Print this page × Export File: RIS (for EndNote, Reference Manager, ProCite) BibTeX. Text. Content: Citation Only. Citation and Abstract. Close × About this article. Cite this article as: Zbigniew J. Witczak, “ Editorial [Hot ...

Henri Ulrich Cumulenes in Click Reactions


Cumulenes are organic molecules with two or more cumulative (consecutive) double bonds. Their reactions often proceed at room temperature, with or without a catalyst, and are stereospecific, giving the reaction products in high yields – features characteristic of “click reactions”. Cumulenes in Click Reactions presents a comprehensive list of cumulene systems and their reactions, with an emphasis on their “click-like” nature. The chapters are structured according to the number of carbon atoms in the system, including coverage of: introduction to the chemistry of cumulenes one-carbon cumulenes: sulfines, sulfenes, thiocarbonyl S-imides, thiocarbonyl S-sulfides, and 1-aza-2-azoniaallene salts two-carbon cumulenes: carbon oxides, carbon sulfides, carbon nitrides (isocyanates, isothiocyanates, and carbodiimides), phosphaallenes, and diarsaallenes 1,2-dicarbon cumulenes: ketenes, thioketenes, ketenimines, 1-silaallenes, 1-phosphaallenes, and other metal allenes 1,3-dicarbon cumulenes: thiocarbonyl S-ylides, 2-azaallenium salts, 1-oxa-3-azoniabutatriene salts, 1-thia-3-azoniabutatriene salts, and phosphorous ylides 1,2,3-tricarbon cumulenes: allenes, butatrienes, higher cumulenes and heterobutatrienes noncarbon cumulenes: azides, triazaallenium salts, sulfur oxides, sulfur nitrides, N-sulfinylamines, sulfurdiimides, and dithionitronium cation Cumulenes in Click Reactionsis an essential guide for researchers and advanced students in academia and research working in synthetic organic, inorganic and bioorganic chemistry.

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Zbigniew Zebar In nomine. W imię.

Hani Amouri Chirality in Transition Metal Chemistry


Chirality in Transition Metal Chemistry is an essential introduction to this increasingly important field for students and researchers in inorganic chemistry. Emphasising applications and real-world examples, the book begins with an overview of chirality, with a discussion of absolute configurations and system descriptors, physical properties of enantiomers, and principles of resolution and preparation of enantiomers. The subsequent chapters deal with the the specifics of chirality as it applies to transition metals. Some reviews of Chirality in Transition Metal Chemistry «…useful to students taking an advanced undergraduate course and particularly to postgraduates and academics undertaking research in the areas of chiral inorganic supramolecular complexes and materials.» Chemistry World, August 2009 “…the book offers an extremely exciting new addition to the study of inorganic chemistry, and should be compulsory reading for students entering their final year of undergraduate studies or starting a Ph.D. in structural inorganic chemistry.” Applied Organometallic Chemistry Volume 23, Issue 5, May 2009 “…In conclusion the book gives a wonderful overview of the topic. It is helpful for anyone entering the field through systematic and detailed introduction of basic information. It was time to publish a new and topical text book covering the important aspect of coordination chemistry. It builds bridges between Inorganic, organic and supramolecular chemistry. I can recommend the book to everybody who is interested in the chemistry of chiral coordination compounds .” Angew. chem. Volume 48, Issue 18, April 2009 About the Series Chirality in Transition Metal Chemistry is the latest addition to the Wiley Inorganic Chemistry Advanced Textbook series. This series reflects the pivotal role of modern inorganic and physical chemistry in a whole range of emerging areas such as materials chemistry, green chemistry and bioinorganic chemistry, as well as providing a solid grounding in established areas such as solid state chemistry, coordination chemistry, main group chemistry and physical inorganic chemistry.

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Peter Stang J. Modern Acetylene Chemistry


This comprehensive handbook presents the full potential of modern acetylene chemistry, from organic synthesis through materials science to bioorganic chemistry. K. Houk, H. Hopf, P. Stang, K. M. Nicholas, N. Schore, M. Regitz, K. C. Nicolaou, R. Gleiter, L. Scott, R. Grubbs, H. Iwamura, J. Moore, and F. Diederich – internationally renowned authors introduce the reader, in a didactically skilful manner, to the state-of-the-art in alkyne chemistry. Emphasis is placed on presenting carefully selected and instructive examples as well as essential references to the original literature. Special benefits: Each chapter is rounded off by useful experimental procedures.

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Группа авторов Transition Metals in Supramolecular Chemistry


Perspectives in Supramolecular Chemistry will relate recent developments and new exciting approaches in supramolecular chemistry. In supramolecular chemistry, our aim is to understand molecular chemistry beyond the covalent bond – the series will concentrate on goal-orientated supramolecular chemistry. Perspectives in Supramolecular Chemistry will reflect research which develops supramolecular structures with specific new properties, such as recognition, transport and simulation of biosystems or new materials. The series will cover all areas from theoretical and modelling aspects through organic and inorganic chemistry and biochemistry to materials, solid-state and polymer sciences reflecting the many and varied applications of supramolecular structures in modern chemistry. Transition Metals in Supramolecular Chemistry Edited by Jean-Pierre Sauvage, Université Louis Pasteur, Strasbourg, France The chemistry of weak forces and non-covalent interactions as pioneered by Pedersen, Lehn and Cram is considered to be the origin of modern supramolecular chemistry. 30 years ago transition metals and their complexes were not regarded as important to this science. Transition Metals in Supramolecular Chemistry clearly demonstrates that today, transition metal complexes are routinely used to build large multicomponent architectures which display new and exciting applications including molecular switches, liquid crystals, and molecular magnets. Contents * Ligand and Metal Control of Self-Assembly in Supramolecular Chemistry * Bistability in Iron (II) Spin-Crossover Systems: A Supramolecular Function * Luminescent Sensors with and for Transition Metals * The Chirality of Polynuclear Transition Metal Complexes * Design and Serendipity in the Synthesis of Polynuclear Compounds of the 3d-metals * Rotaxanes: From Random to Transition Metal-Templated Threading of Rings at the Molecular Level * Metallomesogens – Supramolecular Organisation of Metal Complexes in Fluid Phases * Self-Assembly of Interlocked Structures with Cucurbituril Metal Ions and Metal Complexes Reflecting contemporary science, Transition Metals in Supramolecular Chemistry will inspire scientists and students interested in coordination chemistry, magnetochemistry, molecular sensors and switches, liquid crystals and artificial systems.

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